🧪 A team of researchers from the Chinese mainland recently unveiled a groundbreaking model to predict aging in 13 key human organs, from the brain 🧠 to the heart ❤️. Reported on Monday, December 29, 2025 by China Science Daily, this study promises to revolutionize how we understand and tackle aging.
🔍 Previous studies mostly focused on overall aging or single organs, making it tough to decode the distinct genetic and molecular pathways behind each organ's aging process.
🧬 Led by Yang Tielin from Xi'an Jiaotong University, the team performed a genome-wide association analysis and pinpointed 119 genetic loci linked to organ aging. Surprisingly, only 27 loci were shared across multiple organs, highlighting that each organ has its own aging blueprint.
⚙️ The researchers identified 554 genes with high organ-aging risks, each aligning with its organ's unique physiology. From lungs to kidneys, this unveils the core molecular machinery driving aging in different body parts.
💡 Their predictive model proved robust and accurate across diverse populations, paving the way for deeper mechanistic research and future clinical applications.
🩺 Practical perks include early screening for high-risk groups, mapping causal links between organ aging and chronic diseases, and even measuring how smoking speeds up aging in specific organs.
🚀 Published in Nature Communications, this study is a major leap toward personalized anti-aging strategies and smarter healthcare. The future of aging research? It's looking younger than ever! 🌟
Reference(s):
Chinese researchers establish new model to predict human organ aging
cgtn.com
